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临床试验/CTRI/2024/03/064116
CTRI/2024/03/064116尚未招募1/2 期

Ultrasound guided subcostal transversus abdominal plane (TAP) block versus erector spinae plane (ESP) block for post operative analgesia following per cutaneous nephrolithotomy under general anaesthesia

Mahatma Gandhi Medical College And Hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年3月22日最近更新:

试验速览

阶段
1/2 期
状态
尚未招募
入组人数
60
试验地点
1
主要终点
the analgesic effect of subcostal transversus abdominal plane block and erector spine block will be assessed at the end of operation by haemodynamic variability and postoperatively by visual analog scale(VAS), if VAS is more than 4 the patient will receive a rescue dose of 1mg/kg/dose of tramadol.

研究概览

简要总结

post operative pain management is an essential component of anaesthetic management of surgical patient. it ensure patient comfort, fewer cardiac and respiratory complication, early mobilization and hence less chances of deep vein thrombosis. the goal of postoperative pain management is to relieve pain while keeping side effects to a minimum. Even after years of advances, the mainstay of pain therapy is still the opioids. while they are very effective analgesics, opioid also carry with them many undesirable side effects: sedation, respiratory depression, nausea and vomiting, hypotension and and bradycardia, pruritis and inhibition of bowel function. to avoid these newer modalities of pain management are being evaluated. The erector spinae plane (ESP) block is a newer regional anesthetic technique that can be used to provide analgesia for a variety of surgical procedures or to manage acute or chronic pain. it was first described as analgesic therapy for chest neuropathic pain in 2016 .TAP block is most often used to provide surgical anaesthesia for minor superficial procedures on the lower abdominal wall, or post-operative analgesia for processor’s below the umbilicus. It has been proven to be effective for the reduction of postoperative pain intensity after lower abdominal surgery under the umbilicus, especially within 24 h after surgery.

研究设计

研究类型
Interventional
分配方式
Other
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients scheduled for PCNL surgery.
  • Patients of either sex having age 18-65years.
  • Patients who are willing to participate in this study by written and informed consent.

排除标准

  • Patients with ASA physical status grade III/IV Patients with history of drug allergy Infection at local site H/o drug abuse, psychiatric disorder, chronic pain coagulation abnormalities.

结局指标

主要结局

the analgesic effect of subcostal transversus abdominal plane block and erector spine block will be assessed at the end of operation by haemodynamic variability and postoperatively by visual analog scale(VAS), if VAS is more than 4 the patient will receive a rescue dose of 1mg/kg/dose of tramadol.

时间窗: VAS scores will be assessed at intervals of 30 min, 60 min, 2nd hour, 4th hour and then followed fourhourly(8, 12, 16, 20, 24) up to 24 hour postoperatively.

次要结局

  • mean blood pressure, heart rate, patient satisfaction(The effects will be assessed for 24 hrs post procedure)

研究者

申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Vijay Baldaniya

Mahatma Gandhi Hospital and Medical College

研究点 (1)

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