Analgesic Efficacy of Opioid-Free Anesthesia Protocol Combined With Ultrasound-Guided External Oblique Intercostal Plane Block for Laparoscopic Cholecystectomy: A Prospective Randomized Comparative Study
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Assiut University
- Enrollment
- 70
- Primary Endpoint
- the amount of fentanyl consumption used for pain relief in the first six hours after laparoscopic cholecystectomy (LC) under general anesthesia
Study Overview
Brief Summary
laparoscopic cholecystectomy (LC) is often accompanied by moderate-to-severe postoperative pain. opioid-free anesthesia (OFA) consists of a variety of non-opioid narcotic drugs and techniques.
Detailed Description
opioid-free anesthesia (OFA) can control postoperative pain effectively and reduce opioid drug consumption.
The external oblique intercostal plane (EOI) block is easy to perform and may provide effective analgesia for laparoscopic cholecystectomy.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Adult patients scheduled for elective laparoscopic cholecystectomy (LC) surgery under general anesthesia, American Society of Anesthesiologists (ASA) physical status I-II, aged from 18 to 65 years old of either sex
Exclusion Criteria
- •Contraindications to regional block (coagulopathy, infection at the needle insertion site, or known allergy to amide local anesthetics)
- •Pregnancy or breastfeeding women
- •Body mass index (BMI) > 35 Kg/m2
- •History of hepatic, renal, or cardiac disease
- •Chronic opioid use, or history of chronic pain (pain present for more than 6 months)
- •Thoracic deformity
- •Neuropsychiatric disorders
- •Patient refusal.
Arms & Interventions
Group I
Patients will receive ultrasound-guided external oblique intercostal plane (EOI) block added to an opioid-free anesthesia (OFA) protocol
Intervention: EOI with OFA (Procedure)
Group II
Patients will receive an opioid-free anesthesia (OFA) protocol
Intervention: OFA (Drug)
Outcomes
Primary Outcomes
the amount of fentanyl consumption used for pain relief in the first six hours after laparoscopic cholecystectomy (LC) under general anesthesia
Time Frame: The first six hours after surgery
Assessed in microgram
Secondary Outcomes
No secondary outcomes reported
Investigators
Seham Mohamed Moeen Ibrahim
Assiut University
Assiut University