TCTR20200605007
Recruiting
未知
The effects of intermittent hypoxic training on physiological variables in cardiovascular risk persons
Research Affairs, Faculty of Medicine, Khon Kaen University0 sites45 target enrollmentJune 5, 2020
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Hypertension stage 1,
- Sponsor
- Research Affairs, Faculty of Medicine, Khon Kaen University
- Enrollment
- 45
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients age between 30 to 59 years old;
- •2\. Patients with stage I hypertension (a blood pressure of 140\-159/90\-99 mm Hg and of unknown cause) diagnosed by medical specialists according to the JNC8 guidelines in spited of concurrent use of antihypertensive agents;
- •3\. Patients with LDL\-C ≥ 130 mg/dL according to NCEP ATP III (2001\);
- •4\. Patients have body mass index ≥ 23 kg/m2 in overweight, ≥ 25 kg/m2 in obese according to Asia\-Pacific guideline (2008\);
- •5\. Patients had to be under optimal medication treatment for at least six months;
- •6\. Patients had to be clinically stable (i.e. no crises or changes in medication) for at least three months
Exclusion Criteria
- •1\. Patients have a serious respiratory disorder (e.g. asthma, COPD);
- •2\. Patients have a history of cardiovascular diseases (e.g. acute myocardial infarction, and/or unstable angina), history of heart failure and stroke;
- •3\. Patients presenting with history of neuromuscular and musculoskeletal diseases for more than one month;
- •4\. Patients have chronic kidney disease (stage I or more);
- •5\. Patients have type II diabetes mellitus;
- •6\. Patients presenting with endocrine disorders (e.g. hyperthyroidism, hypothyroidism);
- •7\. Woman in pregnancy and lactation;
- •8\. Patients had to be continuous exposure for more than one week to altitudes above 1,000 m during the three months preceding inclusion in the study;
- •9\. Patients who participate in the weight loss program or use of weight loss drugs;
- •10\. Patients with psychology signs and symptoms (e.g. anxiety, depression)
Outcomes
Primary Outcomes
Not specified
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