NCT00893191Unknown不适用
The Effect of Sildenafil on Sleep-Disordered Breathing in Obese Patients With Sexual Dysfunction
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- apnea hypopnea index after sildenafil vs. placebo
研究概览
简要总结
Sildenafil has been shown to aggravate sleep-disordered breathing in patients with severe obstructive sleep apnea. The aim of the present study is to examine the frequency of sleep-disordered breathing in obese patients who are candidates for treatment with sildenafil for sexual dysfunction. In addition we wish to assess the effect of sildenafil on sleep-disordered breathing.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 65 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Age - 40-65 years
- •BMI equal to or over 30
排除标准
- •A known cardiorespiratory, liver or kidney disease
- •Treatment with nitrates or alfa blockers
- •Performed polysomnography in the past
结局指标
主要结局
apnea hypopnea index after sildenafil vs. placebo
时间窗: Hours
次要结局
- Sleep parameters (latency, efficiency etc) following sildenafil vs. placebo(hours)
研究者
研究点 (1)
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