Effects of Mild Hypobaric Hypoxia on Sleep and Post-sleep Performance
Not Applicable
Completed
- Conditions
- Environmental Sleep DisorderAltitudeHypoxia
- Registration Number
- NCT00498563
- Lead Sponsor
- Oklahoma State University Center for Health Sciences
- Brief Summary
Hypobaric hypoxia (decreased oxygen supply to body tissues due to low atmospheric pressure) caused by exposure to high altitude disrupts sleep. Sleep deprivation is associated with degraded post-sleep performance of neurobehavioral tasks. The lowest altitude at which sleep and/or post-sleep performance are affected is not known. The study hypothesis is that sleep and/or post-sleep performance of neurobehavioral tasks will occur due to hypobaric hypoxia at altitudes of 8,000 or less.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 34
Inclusion Criteria
- healthy
- age 30 to 60 years
Exclusion Criteria
- sleep disorders or abnormal sleep patterns
- mood or psychiatric disorders including claustrophobia
- altitude exposure above 5,000 ft in the previous 2 months
- born or raised at terrestrial altitude 5,000 ft or greater
- conditions that would disqualify for FAA Medical Certificate
- acute medical conditions
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Quality and quantity of sleep measured by actigraphy and polysomnography Neurobehavioral performance measured by Psychomotor Vigilance Test (PVT) and Automated Neurophysiologic Assessment Metrics Battery (ANAM) 7 hours; 4 hours
- Secondary Outcome Measures
Name Time Method Mood State measured by Profile of Mood States (POMS) Symptoms of altitude illness measured by Environmental Symptoms Questionnaire (ESQ IV) and Lake Louise Symptom Scores (LLS) 20 hours
Trial Locations
- Locations (1)
Oklahoma State University Center for Aerospace & Hyperbaric Medicine
🇺🇸Tulsa, Oklahoma, United States