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The effectiveness of infusion of ascorbic acid and thiamine on the clinical implications of severe sepsis patients admitted to IC

Phase 2
Conditions
Sepsis.
Sepsis, unspecified
Registration Number
IRCT20130812014333N78
Lead Sponsor
Vice chancellor for research of Kermanshah University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

Dysfunction of organs and SOFA score = 2 in patients whose antibiotic therapy is diagnosed.
SOFA score = 2 in patients whose antibiotic therapy is diagnosed.

Exclusion Criteria

Pregnant women and people under the age of 18; ;
Allergy to ascorbic acid, Chronic hemodialysis, Hemochromatotomy
Sickness to G6PD
Nephropathy oxalate or bilateral erlithiasis
Receive simultaneously other antioxidants
Patients with acquired immunodeficiency disease

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Organ dysfunction. Timepoint: The first day and fourth day study. Method of measurement: Based on laboratory and clinical criteria.;Length of stay in ICU. Timepoint: 28 days after intervention. Method of measurement: Based on patient records.;Mortality rate. Timepoint: 28 days after intervention. Method of measurement: Based on patient records.
Secondary Outcome Measures
NameTimeMethod
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