Multi-center Ocular Biological Parameters Study

• Conditions: Cataract

• Registration Number: NCT04340635
• Lead Sponsor: Aier School of Ophthalmology, Central South University

Brief Summary

This study is a multi-center study, which collects data from multiple regions to obtain the general biological characteristics of the Chinese population. The formula for calculating the artificial lens power based on foreign populations is effectively modified based on the Chinese population.

Detailed Description

①Relevant domestic studies on the biological characteristics of the eye are mainly limited to a certain city and region. Most of the studies that represent the biological characteristics of the general population in China and the differences in biological parameters at home and abroad are in the research process, or Semi-finished products.

②The investigators found in clinical observation that the eyeball biological data of the Chinese population may not be consistent with the foreign population.

③ This study is the first study of human eye biological parameters based on different regions of large-scale populations in China, which is of great significance for understanding the human eye structure in different regions of China.

Study Timeline

• Study Start: 2018-01-01
• Study First Submitted: 2020-03-29
• Status Verified: 2020-04
• Study First Submitted QC: 2020-04-07
• Last Update Submitted: 2020-04-07
• Study First Posted: 2020-04-09
• Last Update Posted: 2020-04-09
• Primary Completion: 2020-10-01
• Study Completion: 2020-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20000

Inclusion Criteria

• patients aged over 50 years

Exclusion Criteria

• history of refractive surgery,
• corneal diseases
• ocular inflammation
• trauma

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
axial length (AL)	1 hour	Measured using the partial coherence laser interferometry (IOLMaster, Carl Zeiss Meditec, Germany)
anterior chamber depth (ACD)	1 hour	Measured using the partial coherence laser interferometry (IOLMaster, Carl Zeiss Meditec, Germany)
keratometric power (K)	1 hour	Measured using the partial coherence laser interferometry (IOLMaster, Carl Zeiss Meditec, Germany)
corneal astigmatism (CA)	1 hour	Measured using the partial coherence laser interferometry (IOLMaster, Carl Zeiss Meditec, Germany)

Trial Locations

Locations (1)

Shanghai Aier Eye Hospital; 🇨🇳 Shanghai, Shanghai, China