Effects of Supervised Versus Unsupervised Aerobic Exercise Training on Weight Loss, Functional Capacity, Quality of Life and Depression Level in Patients With Essential Hypertension
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 138
- 试验地点
- 1
- 主要终点
- The functional capacity
研究概览
简要总结
The goal of this observational study is to evaluate the effects of a supervised aerobic exercise training program on weight loss, functional capacity, quality of life (QoL), and depression levels in patients with essential hypertension.
详细描述
Patients who chose the treatment type according to personal preferences were divided into two groups: Group 1(n:91) exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory, and group 2(n:47) was advised to maintain dietary habits and physical activity levels. Body weight, serum lipid levels, functional capacity, QoL, and depression level of all the participants were evaluated at baseline and 6 weeks later.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Over 18 years of age,
- •Absence of concomitant other metabolic and cardiovascular diseases.
排除标准
- •Having suffered an event of ischaemic heart disease (<6 months),
- •Secondary hypertension,
- •Hypertrophic obstructive cardiomyopathy,
- •Congestive heart failure,
- •Uncontrolled cardiac arrhythmia,
- •Thyroid dysfunction,
- •Diabetes mellitus,
- •Symptomatic peripheral arterial occlusive disease,
- •Aortic insufficiency or stenosis,
- •Pulmonary or heart disease with dyspnoea at small or moderate effort,
- •An outbreak of orthopedic problems on hip, knee or ankles, such as arthroplasty, contracture or severe osteoarthritis,
- •Using of antidepressant or anxiolytic drugs,
- •Pregnancy,
- •Cognitive disfunction.
结局指标
主要结局
The functional capacity
时间窗: 6MWT was assessed in face-to-face interviews before and immediately after the treatment was completed.
The 6MWT test and the estimated metabolic equivalents or METs were used performed to evaluate functional capacity.
Body weight
时间窗: was measured at the pre-treatment period and the post-treatment 6th week for all the participants by the same physician.
kilograms
Quality of Life
时间窗: SF36 was assessed in face-to-face interviews before and immediately after the treatment was completed.
Quality of life was assessed with Short Form-36 (SF-36).
Blood samples
时间窗: Twelve-hour fasting blood samples were collected between 6.00 am, and 10.00 am at baseline and week 6.
Serum total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, and triglycerides
Depression level
时间窗: BDI was assessed in face-to-face interviews before and immediately after the treatment was completed.
Depression level was assessed Beck Depression Inventory (BDI).
次要结局
未报告次要终点
研究者
Hasan Kara
Medical Doctor
TC Erciyes University