NCT05035355Unknown不适用
A Spontaneous Breathing Trial-based Protocol-directed Program in Difficult-to-Wean Patients
JinyanXing1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2019年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- mechanical ventilation days
研究概览
简要总结
Weaning patients from a ventilator is one of the most challenging processes in an intensive care unit. The investigators aimed to determine whether spontaneous breathing trial (SBT)-based protocol-directed weaning combined with the high-flow nasal cannula (HFNC) could be superior to routine SBT-based weaning in reducing the duration of mechanical ventilation (MV) in difficult-to-wean patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 16 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age ≥ 16 years old
- •MV for more than 48 hours
- •intubated or tracheostomized
排除标准
- •pregnancy
- •irreversible respiratory failure caused by neurodegenerative disorders, such as Alzheimer disease, motor neuron disease, or multiple system atrophy
- •pre-existing decision to limit life support
- •waiving of MV during treatment
- •terminal stage of severe illness
结局指标
主要结局
mechanical ventilation days
时间窗: 60 days
the duration of mechanical ventilation
次要结局
- re-intubated within 24 hours(24 hours)
研究者
JinyanXing
Director
The Affiliated Hospital of Qingdao University
研究点 (1)
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