A comparison between the efficacy and tolerability of topical sertaconazole and topical terbinafine in localized fungal infections of the ski
- Conditions
- Health Condition 1: null- Localized epidermal dermatophytosis (epidermomycosis)
- Registration Number
- CTRI/2014/09/005029
- Lead Sponsor
- R G Kar Medical College and Hospital Kolkata
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 194
1. Patients aged between 18-65 years
2. Patients of both sexes
3. Patients capable of giving informed consent
4. Patients with localized epidermal dermatophytosis confirmed by presence of fungal hyphae in KOH (potassium hydroxide) preparation of skin scrapings from over the lesion at baseline visit
1. Patients with underlying immunosuppression
2. Pregnant or lactating women
3. Secondarily infected or eczematized lesions
4. Lesions over multiple anatomical regions
5. Lesions with nail or scalp involvement
6. Patients who received any type of anti-fungal therapy within 30 days prior to baseline visit
7. Patients who applied any other topical agent over the lesions prior to baseline visit
8. Patients incapable of understanding the protocol
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Complete clinical cure defined as complete absence of erythema, scaling and pruritus and overall global assessment. <br/ ><br>2. Mycological cure defined as absence of fungal hyphae in KOH preparation of skin scrapings from over the lesion.Timepoint: 2 and 4 weeks after randomization
- Secondary Outcome Measures
Name Time Method ocal adverse effects such as dryness, irritation, eczema, tenderness.Timepoint: 2 and 4 weeks after randomization;Scores of erythema, pruritus, scalingTimepoint: baseline, 2 and 4 weeks after randomization