Bloodless Reperfusion in Acute Myocardial Infarction Pilot Study
- Conditions
- 10011082Acute myocardial infarctionheart attack
- Registration Number
- NL-OMON48480
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
Patients with an acute STEMI are eligible when they meet the following
inclusion criteria: Symptom onset < 6 hours, Thrombolysis In Myocardial
Infarction (TIMI) 0 flow, and at least 1 intermediate lesion in a non-infarct
related artery. Patients need to be hemodynamically stable, responsive and
compos mentis.
Exclusion Criteria
Major exclusion criteria are cardiogenic shock and a history of prior
myocardial infarction or coronary artery bypass grafting (CABG).
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>30-day major cardiac and cerebral events (MACCE), including peri-procedural<br /><br>complications<br /><br>Time from start bloodless reperfusion technique (i.e. proximal balloon<br /><br>inflation) to PCI<br /><br>Coronary wedge pressure (CWP) before saline infusion compared with CWP directly<br /><br>after saline infusion (prior to the actual opening of the infarct related<br /><br>artery), representing acute cardioprotection</p><br>
- Secondary Outcome Measures
Name Time Method