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Myocardial perfusion scintigraphy in acute myocardial infarction patients treated with successful percutaneous coronary interventio

Not Applicable
Conditions
Acute Myocardial Infarction
Registration Number
JPRN-UMIN000002798
Lead Sponsor
Division of cardiology,Department of Internal Medicine. St.Marianna Uneversity School of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
100
Inclusion Criteria

Not provided

Exclusion Criteria

Patients who had acute coronary syndrome within the last half year, those with severe hepatic and/or renal impairment, those with inappropriate arrhythmia, such as premature ventricular contraction (PVC) and atrial fibrillation, for electrocardiography-gated SPECT data collection, and small heart patients.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1.Hematological evaluation Creatinine kinase (CK), CK-myoglobin binding (CK-MB), brain natriuretic peptide (BNP), creatinine (Cr) 2.Myocardial planner images Planner images obtained in the early and delayed phase after tracer injection 3.Myocardial single photon emission computed tomography (SPECT) Short-axis SPECT images at rest 4.Gated SPECT Left ventricular (LV) end systolic and diastolic volumes, LV ejection fraction, LV diastolic function
Secondary Outcome Measures
NameTimeMethod
1.Planner images in the lower extremities (using 99mTc-MIBI) Images in the upper and lower thighs obtained at the early phase after tracer injection 2.Cardiopulmonary exercise testing Systolic and diastolic blood pressures at rest, at warming up, during exercise, at peak exercise and cooling down, pulse, a respiratory rates (RR), minute ventilation (VE), oxygen uptake (VO2), a carbon dioxide production rate (VCO2), the relation between ventilation and VO2 (VE/ VO2), the relation between ventilation and VCO2 (VE/VCO2), anaerobic threshold (AT), peak VO2, VE/VCO2 slope, VO2/WR, end-tidal oxygen tension pressure (PETO2), end-tidal carbon dioxide pressure (PETCO2)
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