Analgesia provided by intravenous paracetamol compared with intravenous morphine, for pain secondary to isolated limb trauma, in the emergency department: a pilot randomised trial

Completed

• Conditions: Isolated limb trauma; Signs and Symptoms

• Registration Number: ISRCTN52451941
• Lead Sponsor: nited Bristol Healthcare NHS Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-08-29
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Isolated limb trauma
2. Moderate to severe pain, with initial verbal pain score of 7 or more
3. Age >15 and <65 years
4. Weight >50 kg

Exclusion Criteria

1. Chest pain
2. Glasgow Coma Scale (GCS) <15
3. Allergy to morphine or paracetamol
4. Known liver disease, or patient clinically jaundiced
5. Major Trauma
6. Known pregnancy
7. Breast feeding
8. Patients requiring an immediate limb-saving procedure
9. Age <16 or >65 years
10. Patients in extreme distress who are unable to consent
11. Communication difficulties (foreign language, prior confusion) preventing informed consent or co-operation with pain scoring

Study & Design

• Study Type: Interventional
• Study Design: Not specified