The use of intravenous paracetamol (acetaminophen) infusion before the start of general anesthesia with spectral entropy monitoring decreases consumption of the inhalational anesthetic sevoflurane in patients undergoing thyroidectomy surgery.
Completed
- Conditions
- anesthesiology for thyroidectomy.Anaesthesiology - Anaesthetics
- Registration Number
- ACTRN12613000485730
- Lead Sponsor
- dr. waleed m abdelmageed
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 62
Inclusion Criteria
ASA physical status I and II patients of both sex, scheduled for subtotal thyroidectomy under general anesthesia.
Exclusion Criteria
known allergy to paracetamol, neurological or psychological diseases, impaired liver functions (ALT > twice the normal value) and impaired renal function (serum creatinine >2.0 mg %). Exclusion criteria also included pregnancy and breast feeding, the chronic use of analgesics or drugs affecting the central nervous system (CNS) function, the use of paracetamol within 6 hours or any other analgesic medication within 12 hours before the operation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method