To compare a drug (paracetamol) with another (dexamethasone) given either in vein or inhaled as vapour in preventing sore throat after operatio
Not Applicable
- Conditions
- Health Condition 1: K802- Calculus of gallbladder without cholecystitisHealth Condition 2: K802- Calculus of gallbladder without cholecystitis
- Registration Number
- CTRI/2019/02/017541
- Lead Sponsor
- Safdarjung Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients fulfilling the criteria of American Society of Anesthesiologists Physical Status I and II adults
2. scheduled for elective laparoscopic cholecystectomy under general anaesthesia with tracheal intubation.
3. Either gender, aged 18-65 years
Exclusion Criteria
1. Patients with a history of recent respiratory tract infection or sore throat within <2 weeks
2. Patients with anticipated difficult intubation
3. Patients receiving analgesic or steroid therapy or known allergy to study drugs
4. Patients with diabetes, obesity, cardiac, respiratory, hepatic or renal disease
5. Pregnant women
6. Surgery duration greater than 3 hours
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence of postoperative sore throat in patients receiving preoperative intravenous paracetamol and a combination of paracetamol with nebulised or intravenous dexamethasoneTimepoint: At recovery 0,1, 6, 12 and 24 hours postoperatively
- Secondary Outcome Measures
Name Time Method 1. To compare the severity of postoperative sore throat among the three groups. <br/ ><br>2. To compare the incidence of hoarseness of voice and cough among the groups. <br/ ><br>Timepoint: At recovery 0,1, 6, 12 and 24 hours postoperatively