Evaluating the effect of intravenous Paracetamol or Diclofenac Sodium suppositories on the need for intravenous narcotic administration for pain relief in patients underwent stomach surgery
Phase 4
- Conditions
- Gastric surgery.Acquired absence of part of stomach
- Registration Number
- IRCT201112078322N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 88
Inclusion Criteria
1. Patients with gastric cancer who are candidate for gastrectomy
2. Age range between 40 to70 years
3. Ability to understand PCA pump use
Exclusion criteria:
1. History of allergy to morphine, acetaminophen, and diclofenac sodium
2. History of heart failure (EF<40%), kidney failure (C2>2), moderate to severe COPD
3. Weight over 10 kilograms or less than 50 kilograms
4. Long-term use of opioids before surgery (for more than 2 weeks continuously)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain intensity. Timepoint: Within the first 24 hours after intervention. Method of measurement: Verbal Analogue Scale.
- Secondary Outcome Measures
Name Time Method evel of Consciousness. Timepoint: Within the first 24 hours after intervention. Method of measurement: Richmond Agitation Sedation Scale (RASS).;Oxygen saturation levels. Timepoint: Within the first 24 hours after intervention. Method of measurement: Pulse oximetry.;Respiratory rate. Timepoint: Within the first 24 hours after intervention. Method of measurement: Counting the number of breaths per minute.;Nausea. Timepoint: Within the first 24 hours after intervention. Method of measurement: Times of nausea and womiting.;Morphine consumption. Timepoint: Within the first 24 hours after intervention. Method of measurement: mg/day.