Effect of a Paracetamol Intravenous Form Versus a Placebo on Morphine Consumption in Patients Undergoing an Open Appendectomy: A randomized double-blind controlled trial
Phase 4
Completed
- Conditions
- patients undergoing open appendectomyIntravenous paracetamol, morphine dosage, appendectomy surgery, post-operative pain
- Registration Number
- TCTR20220615003
- Lead Sponsor
- Burapha University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 88
Inclusion Criteria
1.American Society of Anesthesiologists physical status (ASA) I,II,III
2.spinal anesthesia without opioid was performed
3.able to communicate, use the PCA machine, and rating NRS score
4.no history of drugs allergy to morphine or paracetamol
5.normal AST, ALT and creatinine
6.not pregnant or lactation
Exclusion Criteria
1.opioids was given intraoperative
2.failed spinal anesthesia
3.change the operation
4.other analgesia medication used
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method morphine consumption 4hrs,8hrs,12hrs,24hrs,48hrs total dose (mg)
- Secondary Outcome Measures
Name Time Method pain score pre-opetative,0hr,4hrs,8hrs,12hrs,24hrs,48hrs Numeric Rating Scale (NRS) ,morphine side effect 4hrs,8hrs,12hrs,24hrs,48hrs PONV score, sedation score,paracetamol side effect 4hrs,8hrs,12hrs,24hrs,48hrs yes, no