Does paracetamol given by mouth before wisdom tooth extraction give equal pain relief compared to paracetamol given by intravenous infusion?

Completed

• Conditions: Analgesia in wisdom tooth extraction; Signs and Symptoms; Analgesia

• Registration Number: ISRCTN77607163
• Lead Sponsor: Queen Victoria Hospital NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-05-09
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 116

Inclusion Criteria

Patients over 18 years (either sex) having a general anaesthetic for extraction of wisdom teeth of which at least one must be a lower molar tooth.

Exclusion Criteria

1. Patients who are unable to give full consent, or who do not wish to take part in the trial
2. Patients who have a baseline Visual Analogue Scale (VAS) score of more than zero
3. Patients unable to swallow tablets
4. Patients who have taken simple analgesics that day, prior to surgery
5. Hypersensitivity or history of serious adverse reactions to paracetamol or non-steroidal anti-inflammatory drugs
6. Active liver disease
7. Renal dysfunction
8. Pregnant or breast feeding women
9. Alcohol or drug abuse
10. History of unresponsiveness to paracetamol
11. Gastric or peptic ulcer disease
12. Inflammatory bowel disease
13. Blood coagulation abnormalities

Study & Design

• Study Type: Interventional
• Study Design: Not specified