A Comparison of Pre-Medication with Oral Paracetamol versus Intravenous Paracetamol Given at Time of Induction for Postoperative Analgesia Following Wisdom Tooth Extraction - Oral vs IV Paracetamol for Wisdom Tooth Extractions
- Conditions
- Pain post wisdom tooth extraction
- Registration Number
- EUCTR2008-000427-26-GB
- Lead Sponsor
- Queen Victoria Hospital NHS Foundation Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Patients over 18 having a general anaesthetic for wisdom teeth extractions – at least one of them being a lower tooth.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
o Patients who are unable to give full consent, or who do not wish to take part in the trial
o Hypersensitivity or history of serious adverse reactions to paracetamol or Non-Steroidal Anti Inflammatory
drugs
o Active liver disease
o Renal Dysfunction
o Pregnant or breast feeding women
o Alcohol or drug abuse
o History of unresponsiveness to paracetamol
o Gastric or Peptic ulcer disease
o Inflammatory bowel disease
o Blood coagulation abnormalities
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: Does paracetamol given as a tablet give better pain relief than paracetamol given intravenously in patients having wisdom teeth removed?;Secondary Objective: None;Primary end point(s): We will compare the pain scores of patients in the two study arms one hour postoperatively. This will be done in recovery using a visual analogue scale (VAS) pain scoring system.
- Secondary Outcome Measures
Name Time Method