ACTRN12617000072314已完成1 期
The effect of chitosan-dextran (Chitodex) gel with budesonide and mupirocin in chronic rhinosinusitis patients post endoscopic sinonasal surgery
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 57
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Selection/inclusion criteria:
- •Patients who meet ALL of the following criteria will be offered inclusion in the study:
- •(1)Patients undergoing ESS for CRS AND
- •(2)Have who have had symptoms of chronic rhinosinusitis (nasal discharge, postnasal drip, nasal obstruction, facial pain and pressure, lack of sense of smell) that has been previously persistent for greater than 3 months AND
- •(3)are over 18 years of age AND
- •(4)are able to give written informed consent AND
- •(5)are local patients who will be returning to this centre for postoperative follow-up care
排除标准
- •(1)allergy to shellfish, steroids or mupirocin
- •(2)pregnant or breastfeeding
- •(3)immunodeficient patients (patients on any immunosuppressive or immunomodulatory agent)
- •(4)on other CYP450 inhibiting drugs (e.g. ketoconazole, ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir and telithromycin)
- •(5)liver disease
研究者
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