TO COMPARE 15 ML OF 0.4% LIGNOCAINE VERSUS 3ML OF 2% LIGNOCAINE FOR PREVENTING PAIN ASSOCIATED WITH PROPOFOL INJECTION
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- TO COMPARE 15 ML OF 0.4% LIGNOCAINE VERSUS 3ML OF 2% LIGNOCAINE FOR PREVENTING PAIN ASSOCIATED WITH PROPOFOL INJECTION
研究概览
简要总结
This is a prospective randomized double blind interventional study comparing the effectiveness of two different concentrations and volumes of lignocaine in reducing pain associated with propofol injection. A total of 150 patients scheduled for surgery under general anesthesia will be divided into two groups. Group A will receive 15 ml of 0 point 4 percent lignocaine and Group B will receive 3 ml of 2 percent lignocaine. The Numeric Rating Scale and Withdrawal Response Score will be used to evaluate pain. The study also aims to observe and compare any side effects in both groups. Data will be analyzed statistically with a p value less than 0 point 05 considered significant. The study will be conducted at Dr Susheela Tiwari Government Hospital Haldwani over a period of 18 months
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Double Blind Double Dummy
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients giving informed written consent for participation in study.
- •Patients posted for surgeries under general anesthesia receiving propofol as an induction agent.
- •Age of the patient between 18-65 of either sex.
- •Patients belonging to ASA class I and II.
排除标准
- •Patients with history of any contraindication to propofol or lignocaine.
- •Patients with thrombophlebitis.
- •Patients with history of epilepsy.
- •Patients with psychiatric disorders.
- •Pregnant patients.
- •Patients who had received analgesics prior to anaesthesia.
结局指标
主要结局
TO COMPARE 15 ML OF 0.4% LIGNOCAINE VERSUS 3ML OF 2% LIGNOCAINE FOR PREVENTING PAIN ASSOCIATED WITH PROPOFOL INJECTION
时间窗: Immediately after propofol injection (within 10 seconds)
次要结局
- •To compare Numeric Rating Scale score & Withdrawal Response Score using 15 ml of 0.4 % lignocaine (group A) & 3ml of 2% lignocaine (group B) for preventing pain associated with propofol injection
- •To observe side effects if any & compare amongst the group A & group B.(At baseline immediately post injection 15 minutes post injection & at recovery)