europrotective effect of dexmedetomidine in brain tumor surgery

Phase 3

Recruiting

• Conditions: Cancer; Nervous System Diseases; Anaesthesia

• Registration Number: PACTR202008567047887
• Lead Sponsor: Mona Raafat Elghamry

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-05-16
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

patients aged 20-60 years,
both sex,
ASA class I and II,
who undergo elective supratentorial tumor resection surgery

Exclusion Criteria

patient's refusal,
pre-existing psychiatric disorders or cognitive dysfunction,
cerebral infarction,
frontal lesions
A-V heart block,
patients who need intraoperative blood transfusion or those who need postoperative mechanical ventilation
surgery in prone position.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cerebral oxygen extraction ratio

Secondary Outcome Measures

Name	Time	Method
cognitive function;hemodynamic changes heart rate and mean arterial pressure;complications e.g. PONV, hypotension , bradycardia