CTRI/2020/09/027812尚未招募4 期
Comparison of intravenous Propofol and Etomidate in attenuating the hemodynamic response during laryngoscopy and intubation in trauma patients
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- To determine any difference in objective hemodynamic response (HR, SBP, DBP, MAP) due to IV Propofol and IV Etomidate used during laryngoscopy and intubation in trauma patients.
研究概览
简要总结
It is a study to compare intravenous propofol and intravenous etomidate to blunt the response of heart rate and blood pressure during laryngoscopy and intubation in trauma patient admitted in trauma center
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Inclusion criteria for patients : Patients of either sex with age between 20 to 60 years and body weight 30 to 80 kg belonging to ASA grade 1 and 2, admitted in trauma center receiving no narcotics or sedative drug and who are hemodynamically stable before induction will be included in the study.
排除标准
- •Exclusion criteria : Patient who refuse to participate, patients in shock or if they have any H/o convulsion, allergy to the drug used, respiratory, cardiac, hepatic, or renal dysfunction or if they belong to ASA Grade 3 or 4 will be excluded from the study.
结局指标
主要结局
To determine any difference in objective hemodynamic response (HR, SBP, DBP, MAP) due to IV Propofol and IV Etomidate used during laryngoscopy and intubation in trauma patients.
时间窗: Baseline values of bp ,pulse and MAP ,then one minute after laryngoscopy,then after 5 minutes.
次要结局
- To determine any difference in objective hemodynamic response (HR, SBP, DBP, MAP) due to IV Propofol and IV Etomidate used during laryngoscopy and intubation in trauma patients.(Baseline values of bp ,pulse and MAP ,then one minute after laryngoscopy,then after 5 minutes.)
研究者
研究点 (1)
Loading locations...
相似试验
尚未招募
4 期
Study comparing the difference between Propofol & Etomidate in causing changes to vital parameters of trauma patients while facilitating tracheal intubation for artificial breathingCTRI/2020/09/027812Dr Sampurnand Medical College
已完成
4 期
Comparison of Etomidate, Propofol and Etomidate-propofol Combination in Terms of Effects on Haemodynamic Response to IntubationInduction of AnaesthesiaNCT02186990T.C. ORDU ÜNİVERSİTESİ90
尚未招募
不适用
Studying the effects of two different hypnotic agents (Propofol & Etomidate) on relaxation function of left heartCTRI/2021/06/034090Jawaharlal Institute of Postgraduate Medical Education and Research
已完成
不适用
Comparison of the effects of three intravenous drugs (propofol,etomidate and a 1:1 mixture of propofol and etomidate) on blood pressure,heart rate during injection of study drug and on insertion of endotracheal tube inside trachea during general anaesthesia .CTRI/2017/08/009438Chettinad Hospital and Research InstituteKelambakkamChennai60
Unknown
不适用
Etomidate/Propofol Mixture or Propofol Monotherapy Use in Patients Undergoing General AnesthesiaEtomidate is Mixed With PropofolNCT03855267Guolin Wang200