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Ipilimumab 60-month Pharmacovigilance Protocol for Advanced Melanoma Patients Who Are Hepatitis B and/or Hepatitis C Virus Positive in Taiwan

Completed
Conditions
Hepatitis C
Advanced Melanoma
Hepatitis B
Registration Number
NCT02402699
Lead Sponsor
Bristol-Myers Squibb
Brief Summary

This protocol is being conducted to comply with the direct request from the Taiwan Food and Drug Administration (TFDA) for a 60-month intensive pharmacovigilance protocol of patients with known hepatitis B (HBV) or hepatitis C (HCV) infection, regardless of control on antiviral therapy in Taiwan and who are treated with ipilimumab for advanced (unresectable, recurrent or metastatic) Melanoma.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
3
Inclusion Criteria
  • Age of 18 years or older on date of first dose of Ipilimumab
  • Patients who received at least 1 dose of Ipilimumab for the treatment of unresectable, recurrent or Metastatic Melanoma in Taiwan
  • Patients with advanced Melanoma and HBV or HCV who are initiating Ipilimumab under the discretion of their physician
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Exclusion Criteria
  • Patients who received Ipilimumab as part of a clinical trial
  • Patients who are receiving Ipilimumab for any indication other than local approval (ie, unresectable or Metastatic Melanoma)
  • Patients who are not infected with HBV or HCV
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Identify and describe observed adverse events (AEs) based on liver function abnormalities and changes in hepatitis viral loadDuring 6months after enrollment
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Local Institution

🇨🇳

Taipei 105, Taiwan

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