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Catalyst Pharmaceuticals

Catalyst Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Established
2002-01-01
Employees
167
Market Cap
$2.4B
Website
http://www.catalystpharma.com
Introduction

Catalyst Pharmaceuticals, Inc. is a commercial-stage, patient-centric biopharmaceutical company, which focuses on in-licensing, developing, and commercializing novel medicines for patients living with rare and difficult to treat diseases. The company was founded by Hubert E. Huckel and Patrick J. McEnany in January 2002 and is headquartered in Coral Gables, FL.

Clinical Trials

13

Active:0
Completed:8

Trial Phases

3 Phases

Phase 1:1
Phase 2:5
Phase 3:5

Drug Approvals

3

FDA:3

Drug Approvals

Fycompa

Approval Date
Jan 5, 2024
FDA

AGAMREE

Approval Date
Jan 5, 2024
FDA

Firdapse

Approval Date
Sep 8, 2023
FDA

Clinical Trials

Distribution across different clinical trial phases (11 trials with phase data)• Click on a phase to view related trials

Phase 2
5 (45.5%)
Phase 3
5 (45.5%)
Phase 1
1 (9.1%)

Registry Study to Observe Long-term Safety of Vamorolone (AGAMREE®) in Patients With Duchenne Muscular Dystrophy.

Recruiting
Conditions
Duchenne Muscular Dystrophy
First Posted Date
2024-08-21
Last Posted Date
2025-08-05
Lead Sponsor
Catalyst Pharmaceuticals, Inc.
Target Recruit Count
250
Registration Number
NCT06564974
Locations
🇵🇷

San Jorge Children's Hospital, San Juan, Puerto Rico

🇺🇸

Phoenix Children's Hospital, Phoenix, Arizona, United States

🇺🇸

Arkansas Childrens Hospital, Little Rock, Arkansas, United States

and more 22 locations

Long Term Safety of Amifampridine Phosphate in Spinal Muscular Atrophy 3

Phase 2
Terminated
Conditions
Spinal Muscular Atrophy Type 3
Interventions
First Posted Date
2019-01-28
Last Posted Date
2023-11-30
Lead Sponsor
Catalyst Pharmaceuticals, Inc.
Target Recruit Count
13
Registration Number
NCT03819660
Locations
🇮🇹

Neurological Institute Carlo Besta, Milano, Lombardy, Italy

Controlled Trial to Evaluate Amifampridine Phosphate in Spinal Muscular Atrophy Type 3 Patients

Phase 2
Completed
Conditions
Muscular Atrophy, Spinal
Interventions
Drug: Placebo Oral Tablet
First Posted Date
2018-12-20
Last Posted Date
2021-06-01
Lead Sponsor
Catalyst Pharmaceuticals, Inc.
Target Recruit Count
13
Registration Number
NCT03781479
Locations
🇮🇹

Neurological Institute Carlo Besta, Milano, Lombardy, Italy

Long Term Safety Study of Amifampridine Phosphate in MuSK-MG (Muscle Specific Tyrosine Kinase Myasthenia Gravis)

Phase 3
Terminated
Conditions
Myasthenia Gravis, MuSK
AChR Myasthenia Gravis
Interventions
First Posted Date
2018-07-09
Last Posted Date
2024-05-07
Lead Sponsor
Catalyst Pharmaceuticals, Inc.
Target Recruit Count
63
Registration Number
NCT03579966
Locations
🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

🇺🇸

Univerity of Pennsylvania, Philadelphia, Pennsylvania, United States

🇮🇹

Department of Neuroimmunology and Neuromuscular Diseases Carlo Besta Neurological Institute Via Celoria, Milan, Italy

Study to Evaluate Amifampridine Phosphate in Patients With MuSK-MG

Phase 3
Completed
Conditions
Myasthenia Gravis, Generalized
Interventions
Drug: Placebo Oral Tablet
First Posted Date
2017-10-06
Last Posted Date
2024-03-12
Lead Sponsor
Catalyst Pharmaceuticals, Inc.
Target Recruit Count
93
Registration Number
NCT03304054
Locations
🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

🇺🇸

Univerity of Pennsylvania, Philadelphia, Pennsylvania, United States

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News

Catalyst Pharmaceuticals Secures Patent Protection for FIRDAPSE Until 2035 Through Lupin Settlement

Catalyst Pharmaceuticals and SERB S.A. reached a settlement agreement with Lupin that prevents generic competition for FIRDAPSE (amifampridine) until February 25, 2035.

Catalyst Pharmaceuticals Appoints Dr. William Andrews as Chief Medical Officer to Lead Rare Disease Strategy

Catalyst Pharmaceuticals appointed Dr. William T. Andrews as Chief Medical Officer, succeeding retiring Dr. Gary Ingenito after his successful 10-year tenure with the company.

Catalyst Pharmaceuticals Expands Global Reach with FIRDAPSE Launch in Japan and AGAMREE Review in Canada

DyDo Pharma has launched FIRDAPSE (amifampridine) in Japan for Lambert-Eaton myasthenic syndrome, marking Catalyst Pharmaceuticals' continued expansion of its rare disease portfolio globally.

Santhera's Agamree Receives NICE Recommendation and China NMPA Approval for Duchenne Muscular Dystrophy Treatment

The National Institute for Health and Care Excellence (NICE) has recommended Agamree (vamorolone) for treating Duchenne muscular dystrophy (DMD) in patients aged four and older in England, Wales, and Northern Ireland.

FDA Approves Santhera's Agamree (Vamorolone) for Duchenne Muscular Dystrophy

The FDA has approved Agamree (vamorolone) for treating Duchenne Muscular Dystrophy (DMD) in patients aged two years and older, offering a novel corticosteroid treatment option.

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