The Effects of Ultrasound-guided Serratus Plane Block in Combination With General Anesthesia on Intraoperative Opioid Consumption, Emergence Time and Hemodynamic Stability During Video-assisted Thoracoscopic Lobectomy
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Intraoperative remifentanil consumption
研究概览
简要总结
This study evaluates the effects of serratus plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.
详细描述
Thoracotomy is known as one of the most painful surgery. Thus, there is a development to reduce surgical stress in terms of operation technique, which is video-assisted thoracoscopic surgery. Although it has reduced postoperative pain and complications compared with thoracotomy, VATS is still quite painful operation.
Serratus plane block is a novel technique which provide analgesic effect for lateral chest wall by blocking lateral branch of intercostal nerve. It has been reported to be used for pain management including rib fracture, herpes zoster, and postoperative pain. It has become a popular analgesic modality because it is easy to perform and relatively safe. However, the effect of serratus plane block during intraoperative period has not yet been studied.
In this study, therefore, the investigators decided to assess the effect of serratus plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists physical status classification I-III for three port video-assisted thoracic surgery lobectomy under general anesthesia
排除标准
- •History of allergic reaction to local anesthetics, coagulopathy, local infection at the injection site, and systemic infection.
研究组 & 干预措施
Serratus plane block
The subjects were received serratus plane block in the regional-anesthesia unit out of operation room before induction of general anesthesia. And, video-assisted thoracic surgery was performed under balanced general anesthesia.
干预措施: Serratus plane block (Procedure)
General anesthesia only
Video-assisted thoracic surgery was performed under balanced general anesthesia without serratus plane block
干预措施: General anesthesia only (Procedure)
结局指标
主要结局
Intraoperative remifentanil consumption
时间窗: through study completion, an average of 1 year
Intraoperative remifentanil consumption will be checked.
次要结局
- Dose of rescue drugs used to control blood pressure and HR(through study completion, an average of 1 year)
- Systolic blood pressure(through study completion, an average of 1 year)
- Heart rate(through study completion, an average of 1 year)
- Emergence time(through study completion, an average of 1 year)
研究者
Saeyoung Kim, MD, PhD
Associate professor
Kyungpook National University Hospital