NCT04977440已完成不适用
High Protein Intake During the Early Phase of Critical Illness Compared With Normal Protein Intake
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Effect of high protein intake on serum electrolytes
研究概览
简要总结
This prospective interventional randomized control study was conducted on forty patients with respiratory failure; all patients were intubated and mechanically ventilated for at least three days. Twenty patients received high protein intake using whey protein, with daily follow-up of the blood sugar level, serum electrolytes, and chemistry. ICU outcome regarding food intolerance, 30-day mortality, length of MV and ICU-stay was recorded
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age >18 years
- •Mechanically ventilated patients (for three days or more )
排除标准
- •Age < 18 years old
- •Contraindication for enteral nutrition (gut ischemia, obstruction, or perforation)
- •Expected intolerance for enteral nutrition (paralytic ileus)
- •Inability to start enteral nutrition within 24-hours(i.e. surgery or other interventions)
- •Short bowel syndrome
- •Hemodynamic instability ( i.e shock state, need for vasopressors )
- •Child C liver cirrhosis or acute liver failure
- •Dialysis dependency
结局指标
主要结局
Effect of high protein intake on serum electrolytes
时间窗: up to 7 days
measurements of Na, K, Mg, phosphorous and calcium levels regularly after high protein intake
Effect of high protein intake on glycemic control
时间窗: up to 7 days
measurements of blood glucose levels regularly after high protein intake
次要结局
- Effect of high protein intake on ICU outcome(up to 7 days)
研究者
研究点 (1)
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