High Protein Intake in Critically Ill Ventilated Patients
Completed
- Conditions
- Intensive Care Unit Syndrome
- Registration Number
- NCT04977440
- Lead Sponsor
- Cairo University
- Brief Summary
This prospective interventional randomized control study was conducted on forty patients with respiratory failure; all patients were intubated and mechanically ventilated for at least three days. Twenty patients received high protein intake using whey protein, with daily follow-up of the blood sugar level, serum electrolytes, and chemistry. ICU outcome regarding food intolerance, 30-day mortality, length of MV and ICU-stay was recorded
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Age >18 years
- Mechanically ventilated patients (for three days or more )
Exclusion Criteria
- Age < 18 years old
- Contraindication for enteral nutrition (gut ischemia, obstruction, or perforation)
- Expected intolerance for enteral nutrition (paralytic ileus)
- Inability to start enteral nutrition within 24-hours(i.e. surgery or other interventions)
- Short bowel syndrome
- Hemodynamic instability ( i.e shock state, need for vasopressors )
- Child C liver cirrhosis or acute liver failure
- Dialysis dependency
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effect of high protein intake on serum electrolytes up to 7 days measurements of Na, K, Mg, phosphorous and calcium levels regularly after high protein intake
Effect of high protein intake on glycemic control up to 7 days measurements of blood glucose levels regularly after high protein intake
- Secondary Outcome Measures
Name Time Method Effect of high protein intake on ICU outcome up to 7 days ICU outcome includes ICU survival , mechanical ventilation , food intolerance
Trial Locations
- Locations (1)
Cairo University Hospitals
🇪🇬Cairo, Egypt
Cairo University Hospitals🇪🇬Cairo, Egypt