Gene mutations and -variations in congenital heart defects

• Conditions: congenital cardiovascular malformation; congenital heart defect; 10010394; 10007510

• Registration Number: NL-OMON31069
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 160

Inclusion Criteria

1) Patients with a congenital heart defect, with a variant in the DNA.
2) First degree relatives of patients with a congenital heart defect with a variant in the DNA.

Exclusion Criteria

1) Patients with a congenital heart defect, without a variant in the DNA.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>A genetic variation in relatives, with or without congenital heart defects, of<br /><br>patients with a congenital heart defect and a proven genetic variation.<br /><br>Occurrence of (mild) congenital heart defects in relatives, with or without the<br /><br>genetic variation found in de index patient, of patients with a congenital<br /><br>heart defect and a proven genetic variation.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>