The Effect of Degree of Rice-polishing on Glycaemic Response
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 14
- 试验地点
- 2
- 主要终点
- Glucose
研究概览
简要总结
To investigate the effects of rice polishing on glycaemic and insulinaemic response in healthy Chinese male volunteers.
详细描述
There will be a total of 8 test session. Each session will last for 3.5 hours. At each test session, volunteers will be served with test meal and blood will be collected. After an overnight fast, subjects will visit the research center. Two fasting capillary blood samples will be collected via fingerprick. Following the fasting samples, subject will consume the test meals. Further blood samples will be collected at 15, 30, 45, 60, 90, 120, 150, 180 minutes after the ingestion of test meal. These samples will be used to analyses for whole capillary blood glucose. At every 30 minute interval, samples will be collected for analysis of capillary plasma insulin.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 60 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Chinese ethnicity
- •Age ≥21 and ≤ 60 years
- •Body mass index between 18.5 to 25 kg/m2
- •Normal blood pressure =<140/90 mmHg
- •Fasting blood glucose <6.0 mmol/L
- •In general good health
排除标准
- •Current smoker
- •Have any metabolic diseases (such as diabetes, hypertension etc)
- •Do not have known glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)
- •Have medical conditions and/or taking medications known to affect glycaemia (glucocorticoids, thyroid hormones, thiazide diuretics)
- •Have intolerances or allergies to any foods
- •Currently partake in sports at the competitive and/or endurance levels
- •Intentionally restrict food intake
结局指标
主要结局
Glucose
时间窗: Up to 180 minutes
Whole capillary blood glucose will be measure using Hemocue analyser
次要结局
- Insulin(Up to 180 minutes)
研究者
JeyaKumar Henry
Principal Investigator
Singapore Institute of Food and Biotechnology Innovation