Monitors to Improve Indoor Carbon Dioxide (CO2) Concentrations in the Hospital: a Randomized, Sham-controlled, Open Label Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Time >800 ppm CO2
研究概览
简要总结
Ventilation with fresh outdoor air has recently gained considerable attention as a means to reduce the potential risk of indoor aerosol transmission of respiratory pathogens such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (COVID-19). Commercial carbon dioxide (CO2) monitors are increasingly used in schools, long-term care facilities, offices and public buildings to monitor indoor ventilation. However, no formal evidence is available to support the effectiveness of feedback from CO2 monitoring devices. Moreover, modern hospitals have superior indoor air quality control systems.
The aim of this prospective pilot randomized controlled trial (RCT) is to evaluate whether CO2 monitoring devices would be useful as a means to further maintain lower indoor CO2 concentrations in hospitals.
详细描述
In this pilot, randomized, sham-controlled open-label RCT, hospital rooms will be fitted with Aranet4 Home CO2 sensors.
Each device will continuously measure indoor CO2 concentrations at 1-minute intervals during 4 time periods:
- Baseline: staff blinded to CO2 levels displayed on sensor
2-3. Sham/Intervention period: sensors on the same ward will be randomized to placebo (sensor not showing CO2 levels to staff) or Intervention (sensor displaying CO2 levels to staff) in a cross-over design
- Post-intervention phase (3 weeks post-intervention): staff blinded to CO2 levels
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Double-bed hospital rooms
排除标准
- •Unoccupied rooms
结局指标
主要结局
Time >800 ppm CO2
时间窗: 7 days/time period (pre-, active/sham and post-intervention)
Time/day (in minutes/24h) measuring \>800 ppm CO2
次要结局
- Time >1400 ppm CO2(7 days/time period (pre-, active/sham and post-intervention))
- Time >1000 ppm CO2(7 days/time period (pre-, active/sham and post-intervention))
- Daily peak CO2 concentration [in ppm](7 days/time period (pre-, active/sham and post-intervention))
研究者
Michaël R Laurent, MD PhD
Principal Investigator
Imelda Hospital, Bonheiden