Improving intestinal function after surgery

Phase 3

Completed

• Conditions: Cessation of intestinal motor function post gastrointestinal surgery; Surgery - Other surgery; Oral and Gastrointestinal - Normal oral and gastrointestinal development and function

• Registration Number: ACTRN12605000299606
• Lead Sponsor: Department of Gastrointestinal Surgery, Flinders Medical Centre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-09-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Patients underoing gastrointestinal surgery that involves intestinal manipulation (chiefly colorectal surgery). No recent history of gastrointestinal ulceration, intolerance to nonsteriodal antiflammatory drugs. Creatinine clearance greater than 30 ml/min. No requirement for postoperative ACE inhibitors.

Exclusion Criteria

renal dysfuction, asthma, anticoagulants

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time from operation to passage of flatus and faeces[once daily post surgery for a week];Resumption of liquid and solid food intake[once daily post surgery for a week]

Secondary Outcome Measures

Name	Time	Method
Postoperative vomiting, nasogastric tube usage (and losses per tube if inserted).[daily post surgery for a week];Postoperative renal function [Measured days 1,3,5];Blood loss or perioperative bleeding.[daily post surgery for a week]