TO COMPARE INTRANASAL DEXMEDETOMIDINE WITH KETAMINE AND DEXMEDETOMIDINE COMBINATION IN PAEDIATRIC PATIENTS AS PREMEDICATIO
Not Applicable
- Registration Number
- CTRI/2024/02/062174
- Lead Sponsor
- Vardhman Mahavir medical college and Safdarjung Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Normal airway
2. Elective surgery under general anaesthesia
3. American society of Anaesthesiologists grade I
Exclusion Criteria
Patient at risk of airway obstruction
Patient with known allergy to drug
Patient with neurodevelopment delay
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How do intranasal dexmedetomidine and its combination with ketamine exert their effects in pediatric premedication via alpha-2 adrenergic and NMDA receptor modulation?
What is the comparative effectiveness of intranasal dexmedetomidine versus ketamine-dexmedetomidine combination in pediatric premedication relative to standard-of-care agents like midazolam?
Which pharmacogenomic biomarkers predict response to intranasal dexmedetomidine or ketamine-dexmedetomidine combination in pediatric premedication?
What are the safety profiles and adverse event management strategies for intranasal dexmedetomidine and ketamine-dexmedetomidine combination in pediatric patients?
What alternative premedication combinations involving alpha-2 adrenergic agonists and NMDA antagonists are being explored for pediatric anesthesiology?