Comparison of Granisetron and Ondansetrone on nausea and vomiting in adult patients
Phase 3
Recruiting
- Conditions
- ausea and vomiting in patients admitted to the emergency department.Nausea and vomiting
- Registration Number
- IRCT20191007045013N1
- Lead Sponsor
- Ahvaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Nausea and vomiting in adult patients
Exclusion Criteria
Patients with symptoms such as headaches, lateralized symptoms, and unstable vital signs.
Patients who have chest pain or ECG changes.
Patients with symptoms of Rise ICP.
Patients who have been taking sertonin (eg, fluoxetine, doxepin, isomerboxazide, amitriptyline, etc.) in the past few days.
Patients who have used hepatic cytochrome P450 enzyme stimulating drugs or liver enzyme inhibitors in recent days.
Patients who have consumed grapefruit in the past 24 hours
Patient does not consent to attend or continue treatment.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ausea. Timepoint: 15minute ,30minute,45minute,60minute,75 minute,90minute after to take Granisetron or Ondansetron. Method of measurement: Using a visual analogue scaling method where the patient signs a nausea rate on a line measuring 10 cm in length from zero to ten.;Vomiting. Timepoint: 15,30,45,60,75,90minute after to take Granisetron or Ondansetron. Method of measurement: Count the number of vomiting.
- Secondary Outcome Measures
Name Time Method