comparison of drugs for post operative nausea and vomiting after laproscopic surgeries
Not Applicable
- Conditions
- Health Condition 1: null- PATIENTS UNDERGOING LAPAROSCOPIC SURGERY
- Registration Number
- CTRI/2018/04/012965
- Lead Sponsor
- BPS GMC Khanpur Kalan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.ASA grade I/II patients.
2.Patient receiving general anaesthesia for laparoscopic surgery
Exclusion Criteria
1.Refusal to participate in the study
2.Patients less than 18 or more than 65 years of age
3.Pregnant and lactating females
4.Morbid obesity (BMI >40 kg/m2)
5.Allergy to any of the anti-emetic drugs
6.History of PONV and motion sickness
7.Use of anti-emetic medication within 6 h prior to surgery
8.Use of high dose opioids prior to surgery
9.Patients with history of motion sickness, endocrine or metabolic disorders, hepatic or renal disease, gastrointestinal disorders and psychiatric diseases.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate and compare the efficacy of ondansetron with palonosetron, and ondansetron with granisetron in prevention of Post-Operative Nausea and Vomiting (PONV). <br/ ><br> <br/ ><br>Timepoint: prevention of nausea and vomiting for upto 24 hours after surgery <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1.To compare the side effect and haemodynamic profile on use of ondansetron, palonosetron and granisetron in patients undergoing laparoscopic surgeries under general anaesthesia. <br/ ><br>2.To evaluate patient satisfaction scores. <br/ ><br>Timepoint: INTRAOPERATIVE AND 24 HRS POST OPERATIVE