Pharmakokinetik of Caffeine in Epiretinal Membranes After Oral Intake: a Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- concentration of caffeine in vitreous probes and epiretinal membranes
研究概览
简要总结
Caffeine concentrations in the vitreous Body and exzised epiretinal membranes are measured by gas-chromatography/mass spectrometry.
详细描述
Caffeine concentrations in the vitreous Body and exzised epiretinal membranes are measured by gas-chromatography/mass spectrometry. One hour before surgery patients in the caffeine Group will receive 180mg of caffeine. in all patients vitrectomy with Membrane Peeling will be performed, due to epiretinal membranes
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •epiretinale membrane
排除标准
- 未提供
研究组 & 干预措施
caffeine group
180mg of caffeine will be given orally one jour before vitrectomy with membrane peeling
干预措施: vitrectomy with membrane peeling (Procedure)
control group
no caffeine will be given before vitrectomy with membrane peeling, patients are drinking no coffee in general
干预措施: vitrectomy with membrane peeling (Procedure)
结局指标
主要结局
concentration of caffeine in vitreous probes and epiretinal membranes
时间窗: one hour
concentration of caffeine in the probes will be measuread by gas-chromatography/mass spectrometry
次要结局
未报告次要终点
研究者
Prim. Prof. Dr. Oliver Findl, MBA
Head of Department of Ophthalmology, Professor, MBA
Vienna Institute for Research in Ocular Surgery