Evaluation of Leukocyte Platelet Rich Fibrin With Antimicrobial Photodynamic Therapy in Treatment of Furcation Involvement: Randomised Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- clinical evaluation of vertical pocket depth VPD
研究概览
简要总结
To treat grade II periodontally diseased furcation areas Leukocyte-Platelet Rich Fibrin (L-PRF) combined with antimicrobial Photo-Dynamic Therapy (a-PDT) was used.
详细描述
randomized, triple-blinded study (patient, clinician and biostatistician). Twenty-four patients with Grade II furcation involvement were recruited in this study.
Control group only received L-PRF, while study group used a combination of L-PRF and aPDT Attachment level, pocket depth, horizontal component and gingival recession, also radiographic Bone depth, width, height and volume were were recorded at baseline and postoperatively after 6 months
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 32 Years 至 48 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Grade II furcation involvement
- •age range 18- 50 years
- •3 mm or more vertical probing depth
排除标准
- •systemic disease
- •abnormal clotting and bleeding
- •root caries or restoration
- •Grade II mobility
- •periapical lesions
研究组 & 干预措施
L-PRF
Leukocyte platelet rich fibrin as a sole graft material in class II furcation
干预措施: L-PRF (Procedure)
L-PRF with aPDT
Leukocyte platelet rich fibrin combined with antibacterial photodynamic therapy in class II furcation
干预措施: L-PRF with aPDT (Procedure)
结局指标
主要结局
clinical evaluation of vertical pocket depth VPD
时间窗: 6 months
using periodontal probe in mm
clinical evaluation of gingival recession REC
时间窗: 6 months
using periodontal probe in mm
Clinical evaluation of Vertical clinical attachment level VCAL
时间窗: 6 months
using periodontal probe in mm
clinical evaluation of furcation horizontal component FHC
时间窗: 6 months
using periodontal probe in mm
次要结局
未报告次要终点
研究者
Walid Elamrousy
lecturer of oral medicine and periodontology
Kafrelsheikh University