A randomised trial of propofol sedation versus desflurane anaesthesia, used to supplement spinal anaesthesia, on the quality of recovery following hip replacement surgery in adult patients

Phase 4

• Conditions: Hip surgery; Anaesthesia; Anaesthesiology - Anaesthetics; Surgery - Other surgery

• Registration Number: ACTRN12613000805774
• Lead Sponsor: The University of Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-07-22
• Study Completion: 2016-07-06
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

Adult patients undergoing hip replacement surgery under spinal anesthesia

Exclusion Criteria

Patients, who are not fluent in English will be excluded, as they may be unable to answer the recovery questionnaire adequately. Patients where either general or regional anesthesia is contraindicated, will be excluded

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint will be the incidence of recovery in the cognitive domain of the PQRS at day 3.[Day 3 potoperative]

Secondary Outcome Measures

Name	Time	Method
Recovery for all domains, measured by the postoperative quality of recovery scale (PQRS) at 15 minutes, 40 minutes 1 and 3 days, 1 month and 3 months following cessation of anesthesia. [15 minutes, 40 minutes 1 and 3 days, 1 month and 3 months following cessation of anesthesia];Major adverse events including death, cardiovascular and respiratory complications, intensive care admission, neurological (such as stroke), and infection[Hospital admission]