INcreasing Statin Prescribing in HIV Behavioral Economics REsearch

Not Applicable

Active, not recruiting

• Conditions: HIV; Cardiovascular Diseases
• Interventions: Behavioral: Knowledge assessment; Behavioral: Education Intervention; Behavioral: Provider Feedback

• Registration Number: NCT03687060
• Lead Sponsor: University of California, Los Angeles

Brief Summary

Cardiovascular disease is a major cause of morbidity and mortality among people living with HIV. Recent studies have demonstrated that patients with HIV experience a 50-100% increased risk of myocardial infarction and stroke compared to HIV-uninfected persons. They also face higher risks of stroke, sudden death, and heart failure. However, evidence-based statin therapy-which is safe in this population and highly effective at reducing cardiovascular risk-is under-prescribed. The investigators propose a multi-level intervention to increase evidence-based statin prescribing by addressing barriers at these levels. The implementation intervention includes two strategies: (1) tailored education at the leadership, provider, and patient levels, and (2) behavioral economics-informed feedback for providers.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-09-20
• Study First Submitted QC: 2018-09-25
• Study First Posted: 2018-09-27
• Study Start: 2019-03-04
• Status Verified: 2023-09
• Last Update Submitted: 2023-09-29
• Last Update Posted: 2023-10-02
• Primary Completion: 2023-12
• Study Completion: 2024-03

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• age ≥ 40 years
• have been diagnosed with HIV
• LDL ≥ 190, diabetes and LDL ≥ 70
• or 10-year ASCVD risk ≥ 7.5%
• or history of heart attack, stroke, or peripheral vascular disease
• care for patients with HIV at least 1/2 day each week (physicians)
• work at participating clinics (physicians)

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Exclusion Criteria

• unable to provide written, informed consent
• not at participating clinic

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Provider Level	Knowledge assessment	-
Organization Level	Knowledge assessment	-
Provider Level	Provider Feedback	-
Patient Level	Knowledge assessment	-
Provider Level	Education Intervention	-

Primary Outcome Measures

Name	Time	Method
Change in proportion of PLWH with cardiovascular risk factors seen by a physician receiving statin therapy	12 months

Trial Locations

Locations (8)

Venice Family Clinic; 🇺🇸 Santa Monica, California, United States

Antelope Valley Health Center; 🇺🇸 Lancaster, California, United States

Watts Health Center; 🇺🇸 Los Angeles, California, United States

To Help Everyone Health and Wellness Centers; 🇺🇸 Los Angeles, California, United States

JWCH Institute; 🇺🇸 Commerce, California, United States

Tarzana Treatment Centers, Inc.; 🇺🇸 Tarzana, California, United States

Olive View-UCLA Medical Center; 🇺🇸 Sylmar, California, United States

Oasis Clinic; 🇺🇸 Los Angeles, California, United States