Pain processing and pain assessment in Huntington*s disease A pilot study
- Conditions
- Huntington's Disease and pain10028037
- Registration Number
- NL-OMON56873
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
In order to be eligible to participate in this study, an Adult- Onset
Huntington's Disease (HD) subject must meet the following criteria:
1. Genetically and clinically confirmed AoHD patients (>= 21 years, CAG repeats
>= 36; DCL of 4).
2. Good general health apart from having HD.
Note: Patients with chronic illness (e.g. hypertension) will be eligible if the
illness is stable and well-controlled according to the investigator that will
not impact the primary objectives of the study.
3. Able to give written informed consent.
Potential Adult-Onset Huntington's Disease subject who meets any of the
following criteria will be excluded from participation of this study:
1. Juvenile and Pediatric Huntington*s Disease (age at onset <21 years).
2. Patients in the late stage of the disease (UDHRS-TFC score < 3).
3. Have medical, psychiatric, or other conditions (other than HD) that,
according to the investigator, may compromise the patient*s ability to
understand the patient information sheet, to give informed consent, to comply
with all study requirements, or to perform study assessments .(other than HD).
4. Have a history of (in the past year) or current (ab)use of any drug, alcohol
or medication that, in the opinion of the investigator, may seriously impact
interfere with the primary objectives of the study, according to the
investigator.
5. The presence of any sensorimotor neuropathy or any another disturbance
significantly disturbing the somatosensory systems), based on medical history
and/or clinical examination, that can interfere with the pain testing battery.
6. Women who are pregnant or breastfeeding.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method