Postoperative Pain After Laparoscopic Cholecystectomy in Patients Receiving Bilateral Ultrasound-guided Transverse Abdominis Plane Block Compared With Local Anesthetic Infiltration of Trochar Insertion Sites With Ropivacaine 0.5%
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Pain
- Sponsor
- Baylor College of Medicine
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Pain
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
The purpose if to find out if analgesia with bilateral ultrasound-guided Tranversus Abdominis Plane (TAP) block with Ropivacaine 0.5% is better than analgesia with local infiltration of trochar sites with Ropivacaine 0.5% in patients undergoing laparoscopic cholecystectomy.
Our hypothesis is that in laparoscopic cholecystectomy, bilateral TAP blocks will reduce postoperative pain scores when compared to conventional postoperative pain control with local infiltration of trochar insertion sites.
Detailed Description
The purpose if to find out if analgesia with bilateral ultrasound-guided Tranversus Abdominis Plane (TAP) block with Ropivacaine 0.5% is better than analgesia with local infiltration of trochar sites with Ropivacaine 0.5% in patients undergoing laparoscopic cholecystectomy. Our hypothesis is that in laparoscopic cholecystectomy, bilateral TAP blocks will reduce postoperative pain scores when compared to conventional postoperative pain control with local infiltration of trochar insertion sites.
Investigators
Jaime Ortiz
Assistant Professor of Anesthesiology
Baylor College of Medicine
Eligibility Criteria
Inclusion Criteria
- •Patient ages 18-64
- •American Society of Anesthesiology Physical Status I, II or III
- •Inpatients scheduled to undergo laparoscopic cholecystectomy at Ben Taub General Hospital
Exclusion Criteria
- •Open cholecystectomy - excluded due to increased levels of pain in open procedures
- •Scheduled for ambulatory surgery
- •Renal dysfunction (Serum Cr \> 1.2) - excluded due to potential altered metabolism of anesthetic and pain medications
- •Coagulopathy or anticoagulation - increased risk of bleeding from nerve block injection
- •Allergy or contraindication to any of the study medications or anesthetic agents
- •Chronic opioid analgesic use at home - excluded due to potential difficulty in assessing pain caused by the procedure alone
- •Patient inability to properly describe postoperative pain to investigators (language barrier, dementia, delirium, psychiatric disorder)
- •Patient or surgeon refusal
Outcomes
Primary Outcomes
Pain
Time Frame: 24 hours
Pain scores on NAS scale (0-10) at the following times: Preop, Time 0, Time 1, Time 2, Time 4, Time 8, Time 12, Time 24
Secondary Outcomes
- Narcotics use(24 hours)
- PONV (Postoperative nausea and vomiting)(24 hours)