Postoperative Pain After Laparoscopic Cholecystectomy in Patients Receiving Bilateral Ultrasound-guided Transverse Abdominis Plane Block Compared With Local Anesthetic Infiltration of Trochar Insertion Sites With Ropivacaine 0.5%
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Pain
研究概览
简要总结
The purpose if to find out if analgesia with bilateral ultrasound-guided Tranversus Abdominis Plane (TAP) block with Ropivacaine 0.5% is better than analgesia with local infiltration of trochar sites with Ropivacaine 0.5% in patients undergoing laparoscopic cholecystectomy.
Our hypothesis is that in laparoscopic cholecystectomy, bilateral TAP blocks will reduce postoperative pain scores when compared to conventional postoperative pain control with local infiltration of trochar insertion sites.
详细描述
The purpose if to find out if analgesia with bilateral ultrasound-guided Tranversus Abdominis Plane (TAP) block with Ropivacaine 0.5% is better than analgesia with local infiltration of trochar sites with Ropivacaine 0.5% in patients undergoing laparoscopic cholecystectomy.
Our hypothesis is that in laparoscopic cholecystectomy, bilateral TAP blocks will reduce postoperative pain scores when compared to conventional postoperative pain control with local infiltration of trochar insertion sites.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient ages 18-64
- •American Society of Anesthesiology Physical Status I, II or III
- •Inpatients scheduled to undergo laparoscopic cholecystectomy at Ben Taub General Hospital
排除标准
- •Open cholecystectomy - excluded due to increased levels of pain in open procedures
- •Scheduled for ambulatory surgery
- •Renal dysfunction (Serum Cr > 1.2) - excluded due to potential altered metabolism of anesthetic and pain medications
- •Coagulopathy or anticoagulation - increased risk of bleeding from nerve block injection
- •Allergy or contraindication to any of the study medications or anesthetic agents
- •Chronic opioid analgesic use at home - excluded due to potential difficulty in assessing pain caused by the procedure alone
- •Patient inability to properly describe postoperative pain to investigators (language barrier, dementia, delirium, psychiatric disorder)
- •Patient or surgeon refusal
结局指标
主要结局
Pain
时间窗: 24 hours
Pain scores on NAS scale (0-10) at the following times: Preop, Time 0, Time 1, Time 2, Time 4, Time 8, Time 12, Time 24
次要结局
- Narcotics use(24 hours)
- PONV (Postoperative nausea and vomiting)(24 hours)
研究者
Jaime Ortiz
Assistant Professor of Anesthesiology
Baylor College of Medicine