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Clinical Trials/NCT05310266
NCT05310266
Completed
Not Applicable

Ultrasound-guided Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Appendectomy: A Prospective, Randomized, Controlled Clinical Study

Bakirkoy Dr. Sadi Konuk Research and Training Hospital1 site in 1 country168 target enrollmentApril 6, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Post Operative Pain
Sponsor
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Enrollment
168
Locations
1
Primary Endpoint
Postoperative 24-hours total tramadol hydrochloride consumption
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Laparoscopic appendectomy causes postoperative pain. The primary objective of this prospective randomized controlled study is to compare the effect of ultrasound (US)-guided quadratus lumborum block (QLB) on 24-hour cumulative opioid requirements with transversus abdominis plane (TAP) block.

Detailed Description

168 patients (ASA I-II-III) between 18 and 65 years of age, who were to undergo laparoscopic appendectomy, were randomized and divided into two groups. 32 patients were dropout for different reasons.(68 patients in each of the TAP block and QLB block groups). TAP block was performed for TAP group and QLB block was performed for QLB group. Postoperative analgesia was provided by intravenous tramadol hydrochloride using a patient-controlled analgesia device. 24-hour total tramadol hydrochloride consumption was primary outcome measure.Postoperative numeric rating scale values were the secondary outcome measure.

Registry
clinicaltrials.gov
Start Date
April 6, 2020
End Date
February 21, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Responsible Party
Principal Investigator
Principal Investigator

Gokhan Sertcakacilar, MD

Principal investigator

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Eligibility Criteria

Inclusion Criteria

  • Ages of 18-65
  • Patients who will undergo laparoscopic appendectomy
  • ASA I-II-III patients

Exclusion Criteria

  • Clinically known local anesthetic allergy
  • Morbid obesity (body mass index\>40 kg m2)
  • Clinically diagnosis of opioid, alcohol and substance dependence
  • Clinically diagnosis of psychiatric disease
  • Coagulopathy
  • Patients with ASA IV-V

Outcomes

Primary Outcomes

Postoperative 24-hours total tramadol hydrochloride consumption

Time Frame: 24 hours postoperatively

This will be measured by pca device in the 24 hour after

Secondary Outcomes

  • Numerical rating scale (NRS) scores of patients(24 hours postoperatively)

Study Sites (1)

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