Transversus Abdominis Plane Block Versus Local Anesthetic Infiltration for Pain Control in the Abdominal Surgery
- Conditions
- Postoperative Pain
- Registration Number
- NCT02029755
- Lead Sponsor
- Taipei Medical University Hospital
- Brief Summary
Postoperative analgesia is an important part of the anesthetic care. According to the recent studies, multimodal analgesia can provide better analgesia \& patient satisfaction with fewer side effect. For example, combining intravenous, intramuscular or oral analgesics with transversus abdominis plane (TAP) block or local anesthetic (LA) infiltration as the multimodal analgesia, can furnish a more effective pain control after the abdominal surgery.
For abdominal surgery, both local infiltration and TAP block target on relieving somatic pain. Local anesthetic wound infiltration is easy to perform with low risk. As the advancement of ultrasound technology, performing the TAP block also becomes easier, safer and more accurate. But whether LA infiltration or TAP block is better for the multimodal analgesia regimen remains unclear.
This study is to compare the postoperative pain score, opioid consumption, side effects, and quality of recovery between these two analgesic methods in patients undergoing abdominal surgery. The investigators hypothesized that TAP block may be more effective than LA infiltration as a part of the multimodal analgesia, and can improve the recovery after the abdominal surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 108
- Adult (20~65y/o)
- American Society of Anesthesiologists (ASA) physical status I~II
- Patients scheduled for regular abdominal surgery under general anesthesia
- ASA physical status ≥ 3
- Allergy to morphine or local anesthetics
- Morphine tolerance
- Drug abuse or addiction
- Bleeding tendency
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Opioid Consumption postoperative 48 hour opioid consumption of the participants will be followed at postoperative 1, 6, 12, 24, 36, 48 hour (up to 48 hours).
Pain Score (NRS: Numerical Rating Scale) postoperative 24 hour dynamic pain scores of the participants will be followed at postoperative 1, 6, 24, 48 hour (up to 48 hours).
(NRS: from 0 to 10, 0 = no pain, 10 = the worst pain) The higher score idicates the worse outcome.
- Secondary Outcome Measures
Name Time Method Sedation Scale postoperative 1, 6, 24, 48 hour Nausea and Vomiting Categorical Score postoperative 1, 6, 24, 48 hour Rescue Antiemetics Use postoperative 1, 6, 12, 24, 36, 48 hour Time to the First Request of Analgesics an expected average of 5 days participants will be followed for the duration of hospital stay
Heart Rate Variability preoperative, postoperative 1 hour and 1 day Length of Hospital Stay an expected average of 5 days participants will be followed for the duration of hospital stay
Time to Flatus an expected average of 5 days participants will be followed for the duration of hospital stay
Number of Participants With Intervention-related Complication an expected average of 5 days participants will be followed for the duration of hospital stay
Rescue Analgesic Use postoperative 1, 6, 12, 24, 36, 48 hour Quality of Recovery 40 postoperative 48 hour Pruritus postoperative 1, 6, 24, 48 hour
Related Research Topics
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Trial Locations
- Locations (1)
Taipei Medical University Hospital
🇨🇳Taipei, Taiwan
Taipei Medical University Hospital🇨🇳Taipei, Taiwan