Ultrasound-guided-transversus Abdominis Plane(TAP) Block Versus Local Anesthetic(LA) Infiltration-the Effectiveness of Post-operative Pain Control in the Abdominal Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Pain
- Sponsor
- Taipei Medical University Hospital
- Enrollment
- 108
- Locations
- 1
- Primary Endpoint
- Opioid Consumption
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Postoperative analgesia is an important part of the anesthetic care. According to the recent studies, multimodal analgesia can provide better analgesia & patient satisfaction with fewer side effect. For example, combining intravenous, intramuscular or oral analgesics with transversus abdominis plane (TAP) block or local anesthetic (LA) infiltration as the multimodal analgesia, can furnish a more effective pain control after the abdominal surgery.
For abdominal surgery, both local infiltration and TAP block target on relieving somatic pain. Local anesthetic wound infiltration is easy to perform with low risk. As the advancement of ultrasound technology, performing the TAP block also becomes easier, safer and more accurate. But whether LA infiltration or TAP block is better for the multimodal analgesia regimen remains unclear.
This study is to compare the postoperative pain score, opioid consumption, side effects, and quality of recovery between these two analgesic methods in patients undergoing abdominal surgery. The investigators hypothesized that TAP block may be more effective than LA infiltration as a part of the multimodal analgesia, and can improve the recovery after the abdominal surgery.
Investigators
hsiao chien tsai
fellow researcher
Taipei Medical University Hospital
Eligibility Criteria
Inclusion Criteria
- •Adult (20\~65y/o)
- •American Society of Anesthesiologists (ASA) physical status I\~II
- •Patients scheduled for regular abdominal surgery under general anesthesia
Exclusion Criteria
- •ASA physical status ≥ 3
- •Allergy to morphine or local anesthetics
- •Morphine tolerance
- •Drug abuse or addiction
- •Bleeding tendency
Outcomes
Primary Outcomes
Opioid Consumption
Time Frame: postoperative 48 hour
opioid consumption of the participants will be followed at postoperative 1, 6, 12, 24, 36, 48 hour (up to 48 hours).
Pain Score (NRS: Numerical Rating Scale)
Time Frame: postoperative 24 hour dynamic
pain scores of the participants will be followed at postoperative 1, 6, 24, 48 hour (up to 48 hours). (NRS: from 0 to 10, 0 = no pain, 10 = the worst pain) The higher score idicates the worse outcome.
Secondary Outcomes
- Sedation Scale(postoperative 1, 6, 24, 48 hour)
- Nausea and Vomiting Categorical Score(postoperative 1, 6, 24, 48 hour)
- Rescue Antiemetics Use(postoperative 1, 6, 12, 24, 36, 48 hour)
- Time to the First Request of Analgesics(an expected average of 5 days)
- Heart Rate Variability(preoperative, postoperative 1 hour and 1 day)
- Length of Hospital Stay(an expected average of 5 days)
- Rescue Analgesic Use(postoperative 1, 6, 12, 24, 36, 48 hour)
- Time to Flatus(an expected average of 5 days)
- Quality of Recovery 40(postoperative 48 hour)
- Pruritus(postoperative 1, 6, 24, 48 hour)
- Number of Participants With Intervention-related Complication(an expected average of 5 days)