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Clinical Trials/NCT05831501
NCT05831501
Completed
Not Applicable

Postoperative Analgesic Efficacy of Trans Abdominis Plane Block in Women Undergoing Caesarean Section, a Randomized Controlled Trial

Armed Forces Hospital, Pakistan1 site in 1 country60 target enrollmentJune 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Post Operative Pain
Sponsor
Armed Forces Hospital, Pakistan
Enrollment
60
Locations
1
Primary Endpoint
Postoperative opioid consumption
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Transverse abdominis plane (TAP) block is an effective method to manage postoperative pain in patients with midline abdominal wall incisions. It is used frequently in many lower abdominal surgeries however its use after caesarean section is still new, and fewer studies are available. We conducted this study to see the analgesic effect of TAP block after caesarean section.

Detailed Description

The study is being conducted, at Combined Military Hospital Sargodha, Pakistan, to compare the analgesic efficacy of TAP block in providing post-caesarean analgesia with the control group, in terms of mean postoperative use of opioids after caesarean delivery. Sixty patients have been randomly selected using non-probability, consecutive sampling, and applying inclusion and exclusion criteria. The study design is a randomized controlled trial with thirty patients in each group undergoing elective caesareans. All patients will be given spinal anaesthesia with 1.5ml of 0.75% hyperbaric bupivacaine for a caesarean section. Patients in Group A will receive bilateral TAP block with 20ml of 0.25% bupivacaine while 20 ml of saline will be injected in patients of Group B on both sides of midline after caesarean section, in addition to intravenous ketorolac 8hrly. The intensity of pain, total opioid consumption, presence of vomiting, and sedation will be noted until 24 hours after the surgery.

Registry
clinicaltrials.gov
Start Date
June 1, 2022
End Date
December 31, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Armed Forces Hospital, Pakistan
Responsible Party
Principal Investigator
Principal Investigator

arshad khushdil

clinical professor

Armed Forces Hospital, Pakistan

Eligibility Criteria

Inclusion Criteria

  • Elective Caesarean section
  • 20yrs to 45yrs

Exclusion Criteria

  • Emergency Surgery
  • known allergy to local anaesthetic
  • severe pre-eclampsia
  • placenta accreta
  • Coagulopathy
  • Hemodynamically unstable

Outcomes

Primary Outcomes

Postoperative opioid consumption

Time Frame: 24 hours post cesarean section

within 24hours after surgery

Secondary Outcomes

  • Pain intensity Score(from end of secarean section till 24 post operative hours)
  • Duration of First Rescue Analgesia(Within 24hours after surgery)
  • Vomiting(Within 24hours after surgery)

Study Sites (1)

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