Effect of Subcostal Transversus Abdominis Plane Block on Early Postoperative Pain in Laparoscopic Cholecystectomy: Randomized, Controlled Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Numerical Rating Scale (NRS) 15 min after entering recovery room
研究概览
简要总结
Transversus abdominis plane (TAP) block has gained popularity for the control of postoperative pain in various surgeries. Three studies showed inconsistent result on pain control after TAP block in laparoscopic cholecystectomy. The TAP technique used in these studies was classic ultrasound guided TAP block. Besides periumbilical incision, sub-xiphoid incision is usually made during laparoscopic cholecystectomy. As typical posterior TAP rarely extend above T8, the investigators undergo subcostal TAP block for this type of surgery. The investigators are going to investigate the effect of subcostal TAP on early postoperative pain after laparoscopic cholecystectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 20-65 patients scheduled elective laparoscopic cholecystectomy
排除标准
- •Patient refusal
- •Allergy to ropivacaine
- •Coagulopathy
- •Morbid obesity (BMI>35 kg/m2)
- •Previous abdominal surgery.
研究组 & 干预措施
Control
Control group receiving saline instead of ropivacaine
干预措施: Placebo Ultrasound guided subcostal TAP block (Procedure)
TAP
TAP group receiving ropivacaine total of 150 mg at TAP under US
干预措施: Ultrasound guided subcostal TAP block (Procedure)
结局指标
主要结局
Numerical Rating Scale (NRS) 15 min after entering recovery room
时间窗: 15 min after entering recovery room
次要结局
- Fentanyl consumption at recovery room(Up to 3 hours until discharge from recovery room)
- Recovery room stay(Up to 3 hours from entering recovery room to discharge)
- Incidence of postoperative nausea and vomiting (PONV)(Up to 3 hours during recovery room stay)
- NRS at 4h, 24h, and 48 h after surgery(4h, 24h, and 48 h after surgery)
研究者
Kim Sang-Hyun
Associate professor
Soonchunhyang University Hospital