Ultrasound Guided Transversus Abdominus Plane Block for Patients Undergoing Laparoscopic Hand-assisted Nephrectomy.

Mayo Clinic1 site in 1 country21 target enrollmentMarch 2010

ConditionsNephrectomy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Nephrectomy
Sponsor: Mayo Clinic
Enrollment: 21
Locations: 1
Primary Endpoint: Determine if TAP block is a viable alternative to PCA narcotics for the control of pain after hand-assisted, laparoscopic nephrectomy.
Status: Completed
Last Updated: 13 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Transversus Abdominus Plane (TAP) block may reduce need for postoperative pain medications in patients undergoing laparoscopic hand assisted nephrectomy. Our hypothesis is that the TAP block will result in a significant reduction in pain scores and morphine requirements in the active group.

Registry

clinicaltrials.gov

Start Date

March 2010

End Date

February 2012

Last Updated

13 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Mayo Clinic

Eligibility Criteria

Inclusion Criteria

•Patients who are ≥ 18 and ≤ 80 years of age.
•Patients scheduled to undergo hand assisted laparoscopic removal of a single kidney for either tumor or living donor transplantation.

Exclusion Criteria

•Patients scheduled to undergo an open procedure for nephrectomy
•Patients who are converted from hand assisted laparoscopic surgery to open surgery due to intraoperative complications.
•Bilateral nephrectomy
•Pregnant or lactating patients
•Patients unable or unwilling to provide informed consent
•Patients unable to comprehend the use of a visual analog scale
•Patients desiring preemptive antiemetics
•Opioid tolerance
•Allergy to amide local anesthetics or any of the study drugs (morphine).
•Contraindication to regional nerve block (bleeding disorder, infection at site of block)

Outcomes

Primary Outcomes

Determine if TAP block is a viable alternative to PCA narcotics for the control of pain after hand-assisted, laparoscopic nephrectomy.

Time Frame: 24 hours postoperatively

Secondary Outcomes

TAP block with ropivacaine will lead to equivalent or better results with regard to the following outcomes:pain scores, nausea, vomiting, sedation, request for PCA, discontinuation of Foley catheter, discharge from the hospital(24 hours postoperatively)