Evaluation of the effect of infusion of GIK (glucose-Insulin-potassium ) solution on serum lactate and central VO2 during CABG surgeries
Phase 2
- Conditions
- Cardiac Surgeries.Cardiac insufficiency Heart failure following cardiac surgery or due to presence of cardiac prosthesis
- Registration Number
- IRCT2015012019470N13
- Lead Sponsor
- Vice Chancellor for Research, Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 74
Inclusion Criteria
age 80-30 years, the first heart surgery, coronary artery bypass graft surgery, the patient informed consent for inclusion; EF less than 40%
Exclusion criteria: Pregnancy; lack of informed consent; patients undergoing dialysis; 200 mmol / L ? Cr; acute coronary syndrome; 5- 350 < FBS; In the circumstances that infusion of GIK will be stopped: 5.5 mmol / L <K increased cardiac markers such as troponin and CPK
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the effect of GIK on serum lactate. Timepoint: At 0-24 and 48 hour after surgery. Method of measurement: Blood sample.
- Secondary Outcome Measures
Name Time Method To determine the effect of GIK on incresing CVO2. Timepoint: At 0-24 and 48 hour after surgery. Method of measurement: ABG of blood sample from central vein.