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Comparison of the effect of ketorolac and morphine on pain control in patients with renal colic

Phase 2
Conditions
Renal colic.
Unspecified renal colic
Registration Number
IRCT20200825048515N40
Lead Sponsor
Shahre-kord University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
272
Inclusion Criteria

age range of 16-65 years
The definitive diagnosis of renal colic (with renal colic symptoms and the presence of stones confirmed by CT)
The weight of 50-100 kg (for the effectiveness of the dose of 30 mg ketorolac)
The pain intensity of equal to or more than 7
The non-drug addiction
The patients’ consent to participate in the study

Exclusion Criteria

Having a history of morphine or ketorolac allergy
Pregnancy or suspected pregnancy
Breastfeeding
Having history of taking painkillers over the last 4 hours
Having a history of underlying diseases
Having traumatic eye or head injuries
Having one kidney or a kidney transplant
Having cerebral hemorrhage or the possibility of its occurrence
Having mental disorders
Having fibromyalgia
Having vascular and brain lesions
Having coagulation disorders, using angiotensin-converting enzyme (ACE) inhibitor or anticoagulants

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pain score. Timepoint: At the beginning of the study and at 5, 15, 30, 60 and 90 minutes after the intervention. Method of measurement: Visual Analogue Scale (VAS).
Secondary Outcome Measures
NameTimeMethod
Mean Arterial Pressure. Timepoint: At the beginning of the study and at 5, 15, 30, 60 and 90 minutes after the intervention. Method of measurement: Monitoring device.;Hear rate. Timepoint: At the beginning of the study and at 5, 15, 30, 60 and 90 minutes after the intervention. Method of measurement: Monitoring device.
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