Comparison of effect of sedoanalgesia using ketamine and midazolam vs midazolam and fentanyl in management of raised intracranial pressure in children due to brain infections
Not Applicable
- Conditions
- Health Condition 1: null- Children aged between 1 to 12 years with raised intracranial pressure due to acute CNS infectionsHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2018/06/014622
- Lead Sponsor
- Pediatric ICU PGIMER Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All children 1-12year old admitted with raised ICP due to acute CNS infections and undergoing invasive intraparenchymal ICP monitoring.
Exclusion Criteria
Acute liver failure
Oliguric AKI
Known hypersensitivity and contraindication to study drugs.
Known chronic neurological illness
Traumatic brain injury, extradural, subdural and subarachnoid haemorrhage, CNS tumours, hydrocephalus
Clinical brain death at admission
Infection at the site of ICP catheter insertion
Hypertensive encephalopathy
Children with more than 7 days of illness
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method