NCT05475041已完成不适用
Simultaneous Resection of Colorectal Cancer and Synchronous Liver Metastases: What Determines the Risk of Unfavorable Outcomes? A Retrospective International Multicenter Study
Fondazione Poliambulanza Istituto Ospedaliero1 个研究点 分布在 1 个国家目标入组 766 人开始时间: 2022年6月30日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 766
- 试验地点
- 1
- 主要终点
- Major complications
研究概览
简要总结
The use of a simultaneous resection in patients with synchronous colorectal liver metastases has increased over the past decades. However, it remains unclear when a simultaneous resection is beneficial and when it should be avoided. The objective of this retrospective study is therefore to compare the outcomes of a simultaneous resection for synchronous colorectal liver metastases in different settings, and to assess which factors are independently associated with unfavorable outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elective minimally invasive or open simultaneous resection of colorectal cancer and synchronous colorectal liver metastases
排除标准
- •(Partially) robotic-assisted or thoracoscopic procedures
- •First stage of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)
- •Patients that underwent major concurrent procedures
结局指标
主要结局
Major complications
时间窗: 30 days postoperatively
Severe complications (Clavien-Dindo grade 3a or higher) related to the surgical procedure
次要结局
- Overall complications(30 days postoperatively)
- Conversion to open surgery(During the surgical procedure)
- Intraoperative incidents(During the surgical procedure)
- Intraoperative blood loss(During the surgical procedure)
- Length of hospital stay(30 days postoperatively)
- Operative time(During the surgical procedure)
- R0 resection margin(30 days postoperatively)
- Red blood cell transfusion(During the surgical procedure)
- Mortality(90 days postoperatively)
研究者
研究点 (1)
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