The Outcomes of Simultaneous Resection for Colorectal Cancer Liver Metastases by Laparoscopic Hybrid Surgery Versus Totally Open Surgery: a Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 266
- 试验地点
- 1
- 主要终点
- short-term outcome: Operative time
研究概览
简要总结
Simultaneous colorectal cancer liver metastasis (SCRLM) is one of the risk factors for poor prognosis in colorectal cancer. Surgical resection of primary and metastatic lesions is the first choice of treatment for patients with resectable SCRLM. Simultaneous resection of colorectal cancer liver metastases by totally open surgery (TOS) has been widely used. However, we propose that laparoscopic hybrid surgery (LHS) may have better short and long-term outcomes. This study aimed to compare the safety, short-term, and long-term efficacy of LHS versus TOS for patients with resectable SCRLMs.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Liver metastasis was detected while the colorectal cancer was diagnosed.
- •Both the primary lesions and liver metastases were confirmed by postoperative pathological examination.
- •Clinical data is complete.
排除标准
- •Patients with unresectable extrahepatic metastases.
- •Patients with other malignant tumor diseases that have not been cured.
- •Clinical and pathological data were missed or incomplete follow-up data.
结局指标
主要结局
short-term outcome: Operative time
时间窗: Within one week of the patient undergoing surgery
Time taken for surgery
short-term outcome: Blood loss
时间窗: Within one week of the patient undergoing surgery
Patient haemorrhage during surgery
short-term outcome: Time of liquid diet
时间窗: Within one week of the patient undergoing surgery
Time for patients to eat fluids for the first time after surgery
short-term outcome: Postoperative hospital stay
时间窗: Within one week of the patient undergoing surgery
Length of stay of patients after surgery
short-term outcome: Surgical complications
时间窗: Within one week of the patient undergoing surgery
Complications that occur in patients after surgery
次要结局
- disease-free survival (DFS)(3years)
- overall survival (OS)(3years)
研究者
Wei Zhang
Department of Colorectal Surgery
Changhai Hospital