The Outcomes of Laparoscopic Hybrid Surgery Versus Totally Open Surgery
- Conditions
- Resectable Simultaneous Colorectal Cancer Liver Metastasis
- Registration Number
- NCT06550700
- Lead Sponsor
- Changhai Hospital
- Brief Summary
Simultaneous colorectal cancer liver metastasis (SCRLM) is one of the risk factors for poor prognosis in colorectal cancer. Surgical resection of primary and metastatic lesions is the first choice of treatment for patients with resectable SCRLM. Simultaneous resection of colorectal cancer liver metastases by totally open surgery (TOS) has been widely used. However, we propose that laparoscopic hybrid surgery (LHS) may have better short and long-term outcomes. This study aimed to compare the safety, short-term, and long-term efficacy of LHS versus TOS for patients with resectable SCRLMs.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 266
- Liver metastasis was detected while the colorectal cancer was diagnosed.
- Both the primary lesions and liver metastases were confirmed by postoperative pathological examination.
- Clinical data is complete.
- Patients with unresectable extrahepatic metastases.
- Patients with other malignant tumor diseases that have not been cured.
- Clinical and pathological data were missed or incomplete follow-up data.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method short-term outcome: Postoperative hospital stay Within one week of the patient undergoing surgery Length of stay of patients after surgery
short-term outcome: Surgical complications Within one week of the patient undergoing surgery Complications that occur in patients after surgery
short-term outcome: Operative time Within one week of the patient undergoing surgery Time taken for surgery
short-term outcome: Blood loss Within one week of the patient undergoing surgery Patient haemorrhage during surgery
short-term outcome: Time of liquid diet Within one week of the patient undergoing surgery Time for patients to eat fluids for the first time after surgery
- Secondary Outcome Measures
Name Time Method disease-free survival (DFS) 3years the time after surgical treatment until the first observation of tumor recurrence or death for any reason
overall survival (OS) 3years the time after surgical treatment until death for any reason
Trial Locations
- Locations (1)
Department of Colorectal Surgery in Changhai Hospital
🇨🇳Shanghai, Shanghai, China
Department of Colorectal Surgery in Changhai Hospital🇨🇳Shanghai, Shanghai, China